ncRNA name | mTOR shRNA |
ncRNA Category | shRNA |
Disease name | choroidal neovascularization (CNV) |
Species | Mus musculus |
Tissues/Cell_line | RPE-choroid complex, neural retinas |
Methods | shRNA knockdown, FFA, immunohistochemistry, RT-PCR |
Expression pattern | associated |
Functional description | Significantly fewer inflammatory cells and less extensive CNV were observed in the animals treated with rAAV-mTOR shRNA when compared with control- and rAAV-scrambled shRNA-treated groups. |
PubMed ID | 28918027 |
Year | 2017 |
Title | Adeno-Associated Viral Vector-Mediated mTOR Inhibition by Short Hairpin RNA Suppresses Laser-Induced Choroidal Neovascularization. |
Drug-related ncRNA | NA |
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